Pramiracetam Dosage, Usage & Benefits

Pramiracetam is part of the racetam family which was first manufactured in Belgium in the 1970s. Most people take it with the expectation of improved mental functions. There is a consensus that Pramiracetam powder is the most powerful in the class of racetams. Most people will start using Pramiracetam powder after starting with weaker racetams.

However if you are experienced at using Aniracetam, Oxiracetam, or Piracetam, then it is key to be aware of the right dosage you need. Since Pramiracetam is concentrated more than 30 times compared to Piracetam, your Pramiracetam dose has to be much more lower in order to receive the same effects.

In this article we will go through most important considerations, such as dosaging, that one should be aware of while using/starting to use Pramiracetam.


  • Heightened memory and clear thinking
  • Reduces stress, anxiety and depression
  • Enhanced mood, focus and perception

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How does Pramiracetam work:

Pramiracetam works in a similar way as other nootropics. It stimulates oxidative catabolism and raises the levels of energy by improving ATP turnover. As a result this increases cAMP levels in the brain. It also increases metabolism of phospholipid and protein biosynthesis.

Pramiracetam also shows its effectiveness by modulating and influencing a number of different receptor sites, including glutamate in the brain. Although this method of action is not fully understood, it is believed Pramiracetam aids in improving the efficiency and reuptake of these channels.

One of the main effects this supplement has is the ability to regulate uptake of Choline into the hippocampus part of the brain which leads to an increase of Acetylcholine neurotransmitter. There have also been many studies conducted looking at Pramiracetam’s ability to increase the amount of communication across the corpus callosum. Researchers are very excited that this might be a possible route to aid in the enhancement of the thought process and creativity.


Pramiracetam is able to increase your mental capabilities and functions with a very few side effects. Unlike other nootropics Pramiracetam has very little effect on mood or anxiety. This is probably because the supplement does not develop substantial amounts of dopamine and GABA in the brain.

As stated above, the most significant benefit is an overall improvement in cognitive functions. Users normally report that their sensory perception level increase following Pramiracetam ingestion.

“Other major benefits reported include an improvement in long-term memory, an enhanced ability to learn, along with increases in logical and thinking abilities.”

Finally, users have stated that Pramiracetam has “unlocked” certain areas of thinking within them that they had not previously recognized. Most researchers believe that majority of these improvements can be explained by the effects the supplement has on the Acetylcholine receptors. This makes it a very effective “brain booster” with very few related site effects.





Typical Pramiracetam dosage:

The advised level of dosage for this supplement is between 200 mg and 400 mg a day. This can be taken all at once or divided equally throughout the day. Unless you have a doctor’s go-ahead, do not go over these dosage levels.

There have been some that have tested taking excessive doses without bad side effects, but it is strongly recommended that you do not do this because of the possibility of a negative reaction. The best course of action would be to test your lowest effective level of sensitivity so that you can plan accordingly.

Side Effects:

Despite Pramiracetam having a greater potency than other racetams, it is generally considered safe with no serious side effects reported. A few side effects that are occasionally reported, which mainly occur because users do not take recommended dosages. These include headaches, drowsiness, and fatigue. In most cases, simply lowering your dosage level will cease any further side effects.