Piracetam and Noopept are commonly compared Nootropics, but what do these supplements actually do? How do they work? Are they safe and what side effects may they have?
Piracetam was the first Nootropic synthesized in 1964. The supplement improves the function of acetylcholine receptors and transmitters in the brain. It is able to easily cross the blood-brain barrier and therefore becomes active quickly after ingestion.
“Acetylcholine is a powerful chemical in the brain that plays a significant role in multiple cognitive functions, such as learning, memory, mood and the thought process”
Due to its ability to increase acetylcholine levels, Piracetam is believed to be very effective. Specifically, Piracetam is famous for improving communication between both hemispheres of the brain. With this come major cognitive benefits that range from an improved memory to better focus and cognition.
In addition, this supplement improves oxygen delivery and uptake by the cerebral cortex. This may explain why Piracetam is used to treat conditions like OCD, epilepsy and post-stroke aphasia. Many experts have also suggested that Piracetam may be effective in the battle against anxiety and depression.
Noopept and its benefits:
Noopept is one of the most recent Nootropics that was originally designed as an improved version of other “older” Nootropics like Piracetam. Its bioavailability is very high which means that more of the supplement is available to be used by the body.
“Noopept is about 1000 to 5000 times more powerful than the original Nootropics.”
Noopept works by attaching itself to the brains glutamate receptors thereby amplifying the effectiveness of the neurotransmitter. Glutamate is another very important brain chemical that is responsible for the functions of memory. Just like Piracetam, Noopept is a supplement that improves the communication between the two hemispheres in the brain.
Noopept is also a neuroprotector which means that it prevents damage to the brain cells and neurons. Many users also experience an increase in alertness, focus, memory and concentration. Another major benefit is an enhanced mental fluidity, thus leading many users being able to read, write, and think with less effort. Studies also show that Noopept leads to feeling more relaxed and less stressed whilst reducing fatigue levels.
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Both supplements are considered to be safe, but it is important to note that due to individual differences (i.e. body shape, size, etc.) these Nootropics will not work exactly the same for everyone. While side effects for Piracetam are rare they range from weight gain, to headaches and cases of nervousness.
Whereas Noopept side effects may include irritation, emotional numbness and nervousness. However, these side effects can be avoided by taking the advised dosage levels.
The recommended dosage for Piracetam is between 1.6 and 9.6 grams a day taken in multiple equal administrations. It is not advised to take Piracetam before you go to sleep.
Because Noopept is many times more potent, the recommended daily dosage is much lower. You should only have between 10 and 30 milligrams a day taken in equal dosages.
So which one should you choose? A decision like this is very personal and is dependent upon your goals and needs. Both supplements are very effective, but you may want to stack Piracetam with Choline supplements.