Picamilon Dosage, Usage, Benefits & Reviews

 picamilon-dosage-2764346Picamilon is a nutritional supplement, used to relieve stress and anxiety. Picamilon is also known as a “feel good” nootropic as it helps to achieve calm and focused state of mind.

Simply speaking, it is a combination of GABA neurotransmitter and Niacin (Vitamin B3). By combining these two nutrients into one formula, scientists discovered it offers a range of cognitive enhancing and neuroprotective effects. More importantly, this vitamin agent works more efficiently than the two supplements taken separately.

Picamilon is a safe and popular nootropic that can be stacked and cycled with other nootropics. In the United Kingdom it is considered a dietary supplement and can be easily bought in health stores or online.

Picamilon is a hybrid nootropic as it is a tranquilizer and a mild stimulant combined into one compound. Picamilon puts the user into a relaxed, stress-free state of mind. Many users take it regularly just for this reason alone.

“Its tranquilizing effects without a sedative component prevent the negative effects of emotional stress, whilst stimulatory effects give a boost in mood, focus and mental energy.”

As a result, people taking this nootropic find it easier to think, make decisions and even get a better, deeper sleep. Picamilon is often used by people who suffer from mood disturbance (irritability), emotional instability and high levels of anxiety.

Health benefits following Picamilon are also evident. It appears to regulate blood pressure, tackle migraines and improve poor cerebral blood flow. Picamilon contains high-efficiency anti-oxidant properties.

History and science behind Picamilon:

Picamilon was developed by Soviet Union scientists back in 1969. The primary purpose of Picamilon was to increase GABA levels in the brain. GABA is an amino acid that works as a neurotransmitter in the brain, promoting calmness and calculated decisions. The problem with GABA is that by itself it is unable to cross the blood-brain barrier.

Therefore, researchers decided to add Niacin to the formula, so GABA was able to cross the blood-brain barriers and reach the brain. Once in the brain GABA is then free to bind to receptors and produce its anxiolytic effect.

Niacin is not only a transporter of GABA but it also has some powerful properties on its own. Being a Vitamin B3, it is essential for your brain because it vasodilates blood vessels thereby increasing the flow of blood and delivery of oxygen and glucose. By increasing a glucose metabolism and energy supply, the brain can work for longer periods of time.

Recommended Picamilon dosage:

New users should begin with a daily dose of 50 mg. If you do not experience any noticeable effects, you should increase it by 50 mg. However, you should never exceed more than 200 mg at once or 300 mg per day.

“Lower doses (i.e. 50 mg/day) provide the anxiolytic and mood-boosting effects, whilst higher doses (i.e. 300 mg/day) are associated with an increased mental energy.”

Picamilon works best if taken on an empty stomach, with its effects becoming apparent in about an hour and lasting up to four hours.

Picamilon’s effects become cumulative and more evident after prolonged use (i.e., several weeks of daily usage). As with other nootropics, Picamilon can be purchased in capsules (typically 100 mg per capsule) or powder form. This latter works out cheaper.


  • Reduces stress and anxiety
  • Effective GABA Derivative
  • Improves quality of sleep and calm

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Picamilon side effects:

Generally, Picamilon is a safe and well-tolerated compound. It has a very low toxicity and no allergenic or carcinogenic properties. The only way its side effects can be experienced is by going over the recommended dose. If it does happen, you may experience occasional headaches, nervousness, dizziness, nausea and low blood pressure. Picamilon can be used on a regular basis and is unlikely to make the user develop tolerance or negative withdrawal effects.


It is a good idea to stack and cycle Picamilon with other nootropics. It may help enhance the effects of other nootropics, such as racetams, as it is believed to be synergistic. Picamilon can be used in cycles with other nootropics, such as Phenibut. While it is very similar in terms of effects, one can develop a tolerance if used daily. That is why cycling it with a much safer Picamilon for a couple of days will be better for you in the long run. However, if you decide to take it with other similar nootropics, you need to remember to reduce the above dosage.


Picamilon is a legal, safe and effective dietary supplement. It can be purchased over the counter in the UK, as well as imported from countries like the USA. Although sold in capsules, it is up to 4 times cheaper to buy it in powder. Key benefits of Picamilon include a reduction in emotional stress, promotion of a relaxed and focused mind, whilst maintaining a good mood. Picamilon can be stacked and cycled with other nootropics. Finally, it does not seem induce tolerance or significant side effects.