By describing the main differences and similarities between Nefiracetam and Oxiracetam this article will help you pick the right nootropic.
Nefiracetam is a nootropic compound which due to structural similarities is often compared to Aniracetam but has a higher potency. Nefiracetam activates the cholinergic, GABAergic and monoamigernic systems. In addition, Nefiracetam helps open calcium channels in the activated neurons which subsequently amplifies the message sent by the neurotransmitters.
Calcium influx is important for the long-term potentiation (LTP). LTP is the process by which signal transmission between the two simultaneously active neurons is strengthened. LTP is demonstrated in the hippocampus, an area of the brain that is especially important in the formation and retrieval of memory.
Nefiracetam also provides a range of cognitive benefits that are associated with other Nootropic supplements. These include an improved memory, learning capacity, and spatial learning.
“Nefiracetam is one of the best supplements for improvements of attention span, focus and concentration.”
This may explain why there is a growing evidence to show that it helps individuals suffering from depression. Finally, Nefiracetam provides neuroprotective benefits, which could have major positive effects in people with drug addiction.
Typical Nefiracetam dosage:
An advised dosage ranges from 5 to 16 mg/kg, which is between 330-1100 mg for a person that weighs 150 pounds. This should be taken in two or three equal doses throughout the day. After oral ingestion the supplement acts fast and reaches the brain within 30 to 60 minute. As with other Nootropics, it will take a few days or weeks before the full effects are actually experienced.
Nefiracetam side effects:
Nefiracetam’s side effects are very comparable to those of other racetams. They include irritability, headaches, fatigue, stomach ailments and nausea. Most cases, however, are not serious and pass very quickly. To overcome the headaches you can add a Choline supplement such as Alpha GPC. Unless used in excessively high doses you should not experience any other side effects.
Oxiracetam and its benefits:
Oxiracetam is a nootropic colloquially known by the terms “brain booster”, “smart pill” or the “study drug”. Oxiracetam is famous for its ability to facilitate learning, memory and improve focus.
“Because of this, Oxiracetam can be thought of as a booster of intelligence that expands memory capacity.”
Oxiracetam increases the blood flow to the brain, thereby improving oxygen and glucose uptake. This ensures a sufficient level of mental energy for a faster and better thought process. You may also experience a more substantial level of alertness throughout your day which would dramatically help with activities such as studying or working.
How does Oxiracetam work:
Our understanding on Oxiracetam’s method of action in the body is still incomplete. However, most researchers believe that it influences the brain’s two key neurotransmitters, Acetylcholine and Glutamate.
Both of them are widely believed to be associated with multiple cognitive processes such as memory formation, thought processing, and learning. After ingestion, the supplement passes through the intestinal tract and reaches maximum levels of bloodstream concentration in about 25 minutes.
Typical Oxiracetam dosage:
The recommended daily dosage is between 600 and 3000 mg. Once in the body, Oxiracetam has a very short lifespan, which is about two and a half hours. Because of this, it is recommended to split your daily dose into smaller equal administrations.
The supplement has proven to be safe and effective as long as you follow the advised dosages. Most people tolerate the supplement and there have been no complaints of dangerous side effects.
Oxiracetam side effects:
Oxiracetam has very little side effects, however the number one reported side effect is a headache. This is caused by an increased demand of Acetylcholine to be transported to the receptor sites. You can prevent this from occurring by stacking Oxiracetam with CDP Choline or Alpha GPC.
Other side effects are insignificant and may include nervousness, nausea, and anxiety, and again most of these only happen when you go past the recommended dosage level.
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Nefiracetam vs. Oxiracetam: Summary
Nefiracetam is a cognitive enhancer that if taken over a prolonged period of time has been shown to improve memory formation. Additionally, Nefiracetam has neuroprotective benefits.
Oxiracetam is another very effective racetam used to enhance learning capacity and prevent against cognitive decline.