GABA Dosage, Usage & Benefits

GABA (gamma-aminobutyric acid) is a naturally occurring neurotransmitter which is produced through glutamate metabolism in the cerebral cortex. GABA is the second most plentiful neurotransmitter in our brains. Although the exact number of neurotransmitters in the body is unknown, experts have been able to estimate that there are over 100 types.

How does GABA work:

GABA has two different ways of working in our bodies. The first way is by maintaining our muscle tone and the second way is by working as an inhibitor within our brain. Therefore, GABA is an inhibitory neurotransmitter which has an inhibitory effect on the central nervous system and reduces the activity of many neurons. GABA deficiencies in the brain may lead to emotional imbalances, including feeling stressed and increased irritability.

image-16-300x200-3942628Typical GABA dosage:

Usually a regular dose of GABA taken is in between 250 mg and 750 mg. This dosage should be taken around two or three times throughout the day, and just like with any other nootropics start off with a lower intake and slowly work your way up until you find a dosage that you comfortable with.

Thus, you should determine the optimal dosage based on an individual sensitivity to it. Although some users have been reported taking higher dosages, it is not recommended. A supplementation of GABA should not supersede any medications prescribed by your doctor, and before taking the nootropic one should have an important discussion with their doctor on whether it is right for them.

“GABA is a popular nootropic that provides relief from symptoms such as ADHD, depression, and anxiety.”

Stress Relief – a recommended dosage should be 250 mg taken twice a day.

ADHD – start off with a dosage of 250 mg and give it two or three days before you increase this.

Insomnia – a recommended dosage should be 500 mg to 700 mg, and should be taken thirty minutes before your usual bedtime.

Fibromyalgiathree times daily with a dosage of 250 mg or once a day at 750 mg.

You should take the supplement while on an empty stomach, and because of the nootropic’s ability to cause drowsiness you should avoid driving. Apart from your brain’s GABA it also influences muscle tone, and if one plans on taking more than 1000 mg a day they should find time to exercise as soon as possible to allow the body to properly process the supplement.

Side Effects:

If taken at the recommended dosage, there should be little potential side effects. Most of the side effects that are reported were usually quite mild and disappeared shortly after onset. Some of them included a prickling in the upper body or limbs, shortness of breath, and an increased heart rate. Since it is not known how GABA affects children, pregnant women should not take the supplement.

GABA alternatives:

Recent studies have shown that GABA is unable to makes its way through the blood-brain barrier. Supplements which do not have the ability to cross this barrier are not used by the brain for this purpose. Individuals who could not benefit from GABA often start using more effective alternatives, such as Picamilon and Phenibut.


  • Reduces stress and anxiety
  • Effective GABA derivative
  • Improves quality of sleep and calm

Read Reviews

View Phenibut Prices

  • Reduces stress and anxiety
  • Effective GABA derivative
  • Improves quality of sleep and calm

Read Reviews
View Picamilon Prices