Best Nootropics for Well-being

It is very common to take nootropics for the sole purpose of enhancing your mood, reducing the feelings of depression and generally improving well-being. Unfortunately, a large proportion of the Western population today is affected by mood issues, anxiety and depression. Recent estimates indicate as much as 10 percent of the population is suffering from similar disorders and this number does not include those who have temporary, milder problems, such as the Seasonal Affective Disorder.

Simply taking a bunch of pills is unlikely to solve everyone’s problems. However, individuals especially with lesser issues could definitely experience a real advantage of a wide range of nootropic supplements that could be included in their routine.

So, which nootropics are the best for mood disorders? Do they cause any side effects? This guide will take you through some of the mood-enhancing nootropics by explaining them in more detail.

Aniracetam is one of the most popular members of the racetam family that is well-known for its positive effects on the user’s mood. People report feeling stimulated, having massive amounts of positive mental energy, concentration and focus. These benefits can be very useful when positivity and motivation are needed to combat depression-like symptoms.

Aniracetam has additional effects, such as helping the blood flow to the brain. The supplement is thought to regulate a number of neurotransmitters. Some researchers even speculate it can aid in a more efficient communication between the hemispheres of the brain.

“This claim is strongly supported by many users who see this as a great way to boost their creativity and holistic thinking.”

If you decide to use Aniracetam remember that it is fat soluble and should be taken with a meal or a glass of milk.


  • Heightened memory and clear thinking
  • Reduced stress anxiety and depression
  • Enhanced mood, focus and perception

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Adrafinil is a synthetic nootropic that is used to treat sleep and attention disorders. Specifically, Adrafinil is the central nervous system (CNS) stimulant that targets the chemical processes within the brain responsible for improving mental focus, energy and increased alertness. Therefore, the main benefit of Adrafinil is the promotion of a wakeful state of mind.

Adrafinil also prevents the breakdown of dopamine and serotonin neurotransmitters. As a result, users experience massive productivity boosts by regulating the mood and reducing stress as their laziness, anxiety and depression are either reduced or completely eliminated.

Adrafinil may be slightly toxic and may cause a negative effect on your liver, especially if used for a prolonged period of time. Even though you can buy Adrafinil online, if you have any concerns about using it you should seek advice from a healthcare professional.


  • Increased alertness and wakefulness
  • Reduced fatigue and tiredness
  • Enhanced mental energy and Productivity

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Noopept is one of the most powerful nootropics on the market. In comparison to Aniracetam, it provides very similar, but even more noticeable effects on the mood. This is linked with the mechanisms of action as Noopept is rapidly absorbed by the body and then easily crosses the blood-brain barrier.

As a result, the effects can be felt within as little as 15 minutes. Evidence suggests that Noopept is able to increase the mental energy, motivation and well-being.

“Advanced nootropic users claim that Noopept is one of the most effective and potent supplements to increase the levels of motivation.”

Additionally, there are scientific studies demonstrating that Noopept has neuroprotective properties. This means that the supplement helps to keep the neurons healthy and fully functioning. In certain cases, Noopept may even be able to reverse the damage neurons as its effectiveness is shown in patients with different cognitive impairments.

These are the main reasons why Noopept is such a good option for improving the mood and alleviating the symptoms of anxiety and depression. Additionally, Noopept is thought to increase and even develop new connections within the brain. This means it can be a great solution for maintaining your brain firing 100% over long periods of time.

  • Heightened memory and clear thinking
  • Reduced stress anxiety and depression
  • Enhanced mood, focus and perception

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Sulbutiamine is a synthetic derivative of thiamine (vitamin B1), which acts in a very similar manner to nootropics. It is understood to have a variety of effects against anxiety and depression. Due to its effectiveness, in some countries Sulbutiamine is even prescribed as a treatment for both of these and any other similar conditions.

After ingestion Sulbutiamine is quickly absorbed by the intestines, the blood system then transports it to the central nervous system (CNS) where it starts to exert its effects. Sulbutiamine is thought to positively affect levels of choline, dopamine and glutamate. These are three very important brain chemicals associated with mood, pleasure, reward, movement and well-being.

“Thus, Sulbutiamine helps to ease stress and fatigue, while boosting the attention and mental alertness.”

For those who suffer from depression, anxiety or related symptoms, this may be a perfect solution.

Inositol (INS):

Inositol has nine isometric forms with myo-inositol (MI) being recognised as having a range of very important biological roles (e.g. cell metabolism, fertility and regulation of cell proliferation). Inositol is found in many foods, such as fruits, nuts, and cereals. However, the levels of Inositol consumed with a diet may be insufficient. Inositol is a very safe dietary supplement which in addition to its biological roles has been effectively used to treat anti-depressant, anxiolytic and anti-panic disorders.

Once Inositol crosses the blood-brain barrier, it starts promoting the production of GABA, a powerful neurotransmitter, mainly responsible for relaxation. Inositol can also aid in increasing the effectiveness of other GABA-boosting supplements by enhancing their binding properties to receptors sites.

High levels of GABA promote a state of calm mind and overall well-being. Thus, Inositol helps to manage the stress levels and normalise the sleep patterns. As a natural solution, it is perfect for many individuals suffering from light anxiety, depression and sleep disorders. Inositol is water soluble and is well tolerated.

The best nootropic for well-being:

The aforementioned substances can effectively help you with your mood, anxiety and depression symptoms. As a result, your well-being will improve. However, each individual reacts to them differently. Therefore, after familiarising yourself with each of them and fully understanding their mechanisms of action you should give one or more of them a try to discover the best nootropic to improve your mood.